Please use this identifier to cite or link to this item: http://ir.library.ui.edu.ng/handle/123456789/2652
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dc.contributor.authorBekibele, C. O.-
dc.contributor.authorBaiyeroju A.M.|| Olusanya, B. A.-
dc.contributor.authorAshaye, A.O.-
dc.contributor.authorOluleye, T. S.-
dc.date.accessioned2018-10-16T12:47:55Z-
dc.date.available2018-10-16T12:47:55Z-
dc.date.issued2008-
dc.identifier.issn0905-222X-
dc.identifier.otherEye 22, pp. 31-34-
dc.identifier.urihttp://ir.library.ui.edu.ng/handle/123456789/2652-
dc.description.abstractBackground: The use of conjunctiva autograft, adjunct antimetabolite therapy has been shown to be effective in preventing pterygium recurrence. Objective: To compare 5 fluorouracil (5-FU) to conjunctival autograft in the treatment of large, fleshy pterygium. Methods: A randomised controlled prospective study of outcome of pterygium treatment using 5-FU as adjuvant treatment compared to conjunctiva autograft. Thirty-five eyes with large pterygium treated with bare sclera conjunctival excision plus 5-FU were compared with 33 eyes treated with excision and conjunctival autograft alone. Results: Post-operative pterygium recurrence was observed in four (11.4%) eyes treated with 5-FU and 4 (12.1%) eyes treated with conjunctiva autograft (P>0.05). The post-operative complications included, granuloma formation 11.4% for 5-FU and 3.0% for autograft and conjunctival discharge 5.7% for 5-FU group only. Conclusion: 5-FU is marginally superior to conjunctival autograft in the prevention of pterygium recurrence but neither gives a more desirable single digit recurrence rate. Randomised studies combining both conjunctival autograft and 5-FU in pterygium treatment is advocated to further explore their effect.en_US
dc.language.isoen_USen_US
dc.publisherNature Publishing Groupen_US
dc.subjectfleshy pterygium;en_US
dc.subjectpterygium recurrence;en_US
dc.subject5-fluorouracil;en_US
dc.subjectconjunctival autograften_US
dc.titlePterygium treatment using 5-FU as adjuvant treatment compared to conjunctiva autograften_US
dc.typeArticleen_US
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